With age, many note a deterioration in memory, sleep quality, loss of concentration and constant fatigue. People have long been in search of additional energy.
Previously, natural ingredients were consumed that made it possible to improve mental performance, energy and concentration.
In the early 1950s, scientists began to experiment with various substances. One of these scientists was Corneliu E. Giurgea.
He was born in 1923 in Romania and was a professor of neurophysiology at the Faculty of Medicine in Bucharest. In USB in Belgium, he was appointed head of the department of neuropharmacology.
In the early 1960s, he conducted research in the search for a sleeping pill associated with the GABAA neurotransmitter. When MMAC was only isolated as a brake neurotransmitter.
V1964 year, synthesizing paracetam (nootropyl) Corneliu E. Giurgea. Paracetam - the first representative of the class of nootropes, until now is the most frequent prescribed drug of this group. Corneliu E. Giurgea found that paracetam (nootropil) tends to activate the brain. So he coined the term Nootropics.
Nootrope is from the Greek noos "mind" + tropeta" conversion. " According to his research and theory of nootropes, these substances improve the performance of healthy people in the brain and restore work in patients with diseases of the nervous system.
Initially, nootropics were used as paraparates for the treatment of depression or neurodegenerative diseases. The nootropic direction of research is very multifaceted. The general goal of these studies is to find new drugs that can directly increase the effectiveness of cognitive, mental activity of the brain, thereby compensating for various neuropsychological deficits. But not exclusively related to aging. Paracetam studies not only enriched the clinic with a new effective agent, but also gave impetus to the search and creation of new highly effective psychotropic compounds with this type of action both among pyrrolidone and among other chemical structures. Currently, Nootrope is also used as a term for synthetic additives that improve mental performance. Neotropic action components are also present in other classes of preparations of different chemical origin
For 2022, nootrophs still do not have an independent class in the international classification of drugs and are pooled with psychostimulants in one group.